Serious? Easy. Set up your project such that beat 2 of the metronome is the first (1) beat of the first bar in your project. You'll have to regroup mentally when your project starts, let the first beat drop (4), and start counting from beat 2 but say '1' instead of '2'. In the metronome setup box you can change the timber and volume, of course, but not for each beat.
Once you start the recording it should be easy..... although in the long run, it's all about how well this idea, accenting 4 instead of 1, serves you.
Cubase 6.5 (6.5.5) and 5.5 (5.5.3), WaveLab Elements 8, iC Pro remote app, LoopMash HD, Win7 64-bit, Intel C2Q9550@2.83GHz, 8G ram, Radeon HD 6570, Gigabyte X48-DS5 MB, Mackie 1640i (FireWire), M-Audio Keystation 61es controller via an M-Audio Midi-Sport 1X1.