Resource (?) issue with Nuendo 5+6 (PC): Can't open plugins

I just had this happen to me last night.

Working on a few projects that were started in Nu5.55, then migrated to Nu6.05
These weren’t giant projects…not even close.

Suddenly I couldn’t add any plugins. When I tried, nothing would happen.
Then I noticed that the ones that were already loaded started opening
with blank interfaces…When I tried to “save the project as” it wouldn’t even
let me change the project name and nothing would happen when I hit the save button…Sometimes the save window wouldn’t even open.

Sounds and seems like a memory issue.
All during the trial with Nu6 I never experienced this and
I put it through some heavy tests.
Now, just days after purchasing the upgrade, I get this nonsense.
Looks like it’s back to 5.5 for me.
The only time I ever experienced anything like this in Nu5
was when the machine was pushed to its absolute limit.
This was not the case last night.

Windows 7 32bit
Gigabyte MB
i7 3770k
12gb (Yea, 8gb just sitting there, waiting)
UAD-2 PCIe (x) 2
RME PCI (Digi 9652)
Nu 6.05
Nu 5.55
Nu 2.33
Nu 1