Hey Grazie,
Panorama sees automatable parameters through Cubase.
Unfortunately you have to tell Omnisphere to make parameters available for host automation before Panorama’s INSTRUMENT mode can see them. Once parameters are available for host automation, you should be able to map them in Panorama’s learn mode and save your new plugin map. You should also save a ‘MIDI Learn template’ in Omnisphere, otherwise Omnisphere will remove the parameters enabled for host control when you change patches.
MIDI learn is a separate system and if you use Omnisphere’s MIDI learn to map a plugin, stick to Panorama’s INTERNAL mode.