There are an awful lot of Amp Sims out there, and very few of them actually sound anything like the item they are supposed to model. I’ve tried Amplitube 3, GTR 3.5, Overloud’s MarkBass, the UAD SofTube & ENGEL amps & various others and whilst they will sometimes work well I honestly think that to start with you will be a lot better off working out your own sound through a real amplifier & getting the tones recorded properly in the first place.
The way I would advise you to go is this:
Firstly, take your favourite guitar to an amp shop and just sit down & try them all -out until you finds the right one for you (and you will know it when you hear it). This may take some time and may also take you down some odd paths - my partner is a bass player and she uses an old Selmer Valve PA head into a 4:12 and a Fender Bassman cab for most stuff but for a little bit of flavour shew also has a Marshall 6100LM Anniversary series (which is effectively 3 amps on one chassis) into the same cabs.
Once you have got “your” sound sorted out, the variety can come either by tracking with a DI or else using 2 different mics - one condenser & one dynamic - and you would be surprised how much tonal variation you will get simply by moving the mics on the cab - experiment with each one on & off axis, nearer & farther away etc. Honestly, this will serve you much better than trying to ram everything through an amp modeller.
This is not to say these tools are no use - not at all - the point I am really trying to make is that to get the best from these tools, you really need to know & understand your own sound to begin with. Why? Simply because with all hardware there are a few well-chosen options that generally all sound pretty good. With digital emulations there are these same options available to you for sure - but the “gotcha” awaiting is that there are thousands of bad settings available and until you have worked out what your sound is the odds are very high you will hit one of the bad sounds much more readily than you will stumble across a good one.
Hope this helps - and also hope it does not come over as a negative post as this is not my intention. 