Nope, not related.
Steve from Soundminer answered me yesterday, and here is the solution, i quote :
You would need to install the Steinberg SKI
Quit all apps. Install SKI
SKI
http://soundminer.s3.amazonaws.com/SMNuendoSpotSKI.bundle(x64,x86,PPC).zipUnzip SKI into
/Library/Application Support/Steinberg/Components (<–create the folder as necessary)Then in Nuendo you should be able to get plug in info and the SKI should show up if its installed properly. Then, launch N5 and v4pro it should show up as Steinberg SKI(in DAW menu of v4pro). Select that to spot.
Working now, except i can’t spot as region (unselectable in SM).