As it happened I just built the same 3930 machine and it is a race horse even w/o OC.
So far I have not done any tweaking to the OS win7 sp1 and if there are no performance problems
comming up I will leave it as it is. Keeping all bits from going into sleep mode might be worth doing, though.
Smaller track count recordings I take in 1.5 ms or 3ms which is fast enough to work with a native reverb in the Nuendo channel sends. But I have done so with a i7 930 machine and the same RME card, already. When mixing it is more the needs of e.g. UADs that lets me choose 256 or even higher. That, I guess, won't change with the faster machine.
Presonus Studio ONE, Harrison Mixbus!, Nuendo 5.5.6 (6.5), WL6 (7), RME, UAD, PoCo, Win7 64, i7 3930K, 16 GB RAM, Intensity, Melodyne, Spectrasonics, VSL, Brainworx, Genelec 5.1, sevaW lla, LAWO, Sony DASH 3324S, 42 RUs of classic hardware & excellent acoustic studio design in new rooms.