This an ongoing problem with Cubase (Mac) and Redline Reverb since C4. Nice folks, great product, but as soon as I open the GUI, it crashes Cubase. Sometimes if I stop playback and wait a second, then open it, I can get by, but in the heat of battle, I don’t always remember and inevitably, it will crash. Unfortunate and from your post, I’m beginning to think it is a Cubase/112db issue, not Mac or PC specific. Good luck