Thank you for your reply BriHar. Im using it in Cubase 7, I thought that was clear from sentence one, but maybe not, then. :stuck_out_tongue: Anyway, I have no problems with it in stand alone, the problem is that there is no e next to the FX in the signal chain under Hardware in the Cubase 7 mixer. Im using UR28M Driver V1.7.2, Cubase 7.0.2 64bit on an iMac OS 10.8.2. Thank you. 