UR 22 Phantom Power Noise

If that’s the case, especially for desktop PCs (and even Laptops), I would pay particular attention to the PC PSU.
Budget PSUs are an ailment to audio PCs - introducing ripple noise harmonics and shortening the life of components (Can you say D e _ _ or H _).
Higher quality active power correction +80% PSUs are the only ones I use in desktops. There are budget power
bricks available for Laptops with inferior components that will not provide stable power day-in & day-out.
60 cycle hum filtered for your listening pleasure!

I always test the output voltages on all new PSUs; e.g. 5v output (+/-) 5% = 4.75v to 5.25%. But, that’s just one part to be concerned over. A PSU is as important as a Preamp in today’s digital world.