UR 22 Phantom Power Noise

Although people often choose to ignore this when I mention it, It can sometimes help by plugging into different USB sockets (and in this case de-reinstalling the driver. You see the various USB ports are generally controlled with different interrupts (IRQs) and depending on what these are shared with, can often be a source of noise, also some ports (often those on the front of the computer) are established with an expansion module, which runs a cable from a connector on the MB to the module - this cable can pick up induced noise.
There’s no guarantee this port switching will work, but it’s worth a try.
Unfortunately the motherboard manuals rarely go into detail these days regarding the manufacturer of the actual chips used on them (we’re not referring to the proverbial “chipset” usually referenced in the manual - this has more to do with the BIOs, and nothing to do with the USB subarchitecture. This can then only be done by visual inspection of the chips themselves on the board, they will usually be in the vicinity of the actual USB risers. Best to get someone familiar with computers on a hardware level to check this.