I use Cubase 7.04 64 bit for any projects involving musicians with instruments. for projects that are vocals over pre-recorded backing tracks, I use studio one v2.6. studio one is unbelievably fast for melodyne use because of ARA. vari audio is good but not as good… I could use studio one for “band” type projects, but find it clunky and ugly for this. regardless of what some say, gui DOES matter if you are using something all day every day like me. i’m happy to switch between both daws depending on the task. studio one has some decent built in plugins but the virtual instruments are poor. but the pro version supports vst standard. best thing apart from melodyne ARA is that you get 5 licenses. unlike Cubase where you only get one. I got studio one pro upgrade from artist for abut £160 so that’s about £32 per machine!
even so, I still prefer Cubase overall, especially when recording and editing multitrack band projects with drums etc. ed