When did it become OK to use USB2 for Audio?

Right.

RME was the first company to make USB 2 interfaces with a low latency performance superior to FW. I believe their first USB 2 product was the Fireface UC, followed by the BabyFace. These interfaces changed the industry and made USB 2 a professional solution. Afterwards, they came out with two more USB 2 interfaces, the Fireface UFX and the Fireface UCX shortly after. The latest product from RME is the MADIFace XT, which is the world’s first (as is usually the case for RME) USB 3.0 interface. This, in my opinion, is the future of audio interfaces. Not sure about Thunderbolt, but USB 3.0 seems to be already going ahead of it in terms of bandwidth and speed from what I’ve read not long ago.

I apologize if I sound like an RME endorser, but they have truly carved the path for other interface companies when it comes to making the impossible possible.