Yes, TotalMix FX is not the most intuitive software ever designed, but neither is Control Room, for the record. Anyhow, both are not too hard to learn, given some time and patience. Like I said before, it all comes down to hardware integration. If you use an RME interface, Control Room basically gives you none at all, while TotalMix FX is completely integrated into your hardware. So, the choice is really an easy one.