I am sorry to hear that the Apple support wasn’t aware of this issue. Apple has already agreed to fix it on their end.
The CoreAudio2ASIO patch is not related to the audio interface but to the software in use. If there is no application installed that needs to be patched, you do not need it. Also, as the UR22 comes with a dedicated driver, you do not need the patch anyway as it is only meant for Class compliant devices.