Anyone know 01v96i latency on USB 2.0?

I’ve Got a kind of same technical issue. Using an old RME hdsp Madi pci-Card With adi-686 adat has far less latency around 2ms than a fireface800 which is around 5ms all digital of course. Can only run properly on rather fast computer i7 and so on. latency values are low 32and48 samples in the control panel. Nuendo and other vst host give me the same overall latency. Is it the ASIO or what giving these delay’s?