Set up UR22 with Cubase 5

Hi, I’ll work with 10-15 tracks (guitars, vocals, midi drums, etc) i’ll try to stick to the 64 samples then, because if I put it on 512 it jumps to 18ms.

It’s a stereo track, i’ve been using cubase for quite a while, and I know all the basic stuff, with my previous sound card (Line6 UX2) I had no problem… I do not understand why is this happening