'Solo' behavior

In some cases, I have had to also activate Solo Defeat on the Output Bus that is being fed by the channel you want to monitor through. The large amount of possible routing paths seems to sometimes confuse Nuendo’s Solo function.

There really is no downside I can find (at least in my usage) from activating Solo Defeat on an Output Bus. I have found that usually does the trick in cases like you are experiencing.

Hope that helps.