I’m in the process of making the jump to Macs, and it’s been outstanding so far. No major hoops to jump through – things tend to work very well so far, on both a Mac Pro and Macbook Pro. I definitely prefer the OSX workflow now. Windows 7 was fine (and still ideal for a VE Pro slave), but I hated Windows 8 and have been feeling a lot of pressure from clients to move to Mac for Pro Tools reasons… so I tried Cubase 7/7.5 on Mac as well, and it works beautifully so far. C7.5 in particular feels quite good on a Mac.
Can’t comment on moving preferences and key commands yet, as I am still adjusting. But I can’t see why you can’t set up things the same way you did before on PC. I’d suggest doing the initial set up manually, though… just to play it safe with moving preference files across platforms, etc…