4 x FD set-up Cubase

If the FDs are not in sequence upon reboot, then you need to put the HW devices themselves in the right order. This should only be necessary once as the sequence should not change thereafter - unless you’re in the habit of disconnecting them - changing their connection sequence on a hub or even changing the port to which a hub is usually connected could cause a change in the sequence.
Changing the sequence is also possible in Cubase Device manager, but can be more confusing and even “messy”. Changing their physical positions is by far the easiest way.