Do you have a reverb or delay turned on within the dspMix FX “app”?
I don’t know how much overlap there is between the UR28M I use and your UR44, but I would open up the “show racks” dialog in Cubase, click on the “Hardware” button there … open up the “Effects Insertion Location” button, and put it to the top position, “Upper position” to see if the delay turns off.
Or simpler, turn off any Delay/Verb turned on in the dspMix FX app.
Sorry if that doesn’t translate well to the UR44.