Sound issue with UR22

I have recently purchased, installed and registered a UR22 audio interface as well as a new HP computer running Windows 8.1 64.
Also part of my set up is a Yamaha PSR-550 keyboard and a Yamaha STAGEPASS 300 output system.
I have followed the installation instructions, viewed the videos for both UR22 and Cubase Ai 8 and I just cannot get sound out of this setup. I must be missing a small click somewhere in either Cubase or the audio interface setup.

Is there someone in this forum that had a similar issue and could help me overcome this problem.

Thanks

Mel Long