Does VPN use adversely affect DAW activities?

Its the same from me. The most common is fb or sometimes even gmail, its quite bothersome. But for DAW, I have never experienced any changes, I use that one but considering to replace it soon. Maybe it also differs from the vpn? I have heard that when you watch netflix, then the streaming service has blocked some common private network IPs, does anybody knows if there is something similar with DAWs?