Cannot connect Input Alesis Multimix 4 USB FX to Cubase 8

It gives me the option of the device in the drop down but it doesn’t pick it up when I click on it. I have switched everything off and on again, I cannot find the reason why it wouldn’t pick it up. The only thing that sprang into my mind was that I am using a USB connection to the Alesis that is of lower quality?
Cheers, Simone