I run my Virus TI through a USB on my motherboard. My motherboard has USB 3, they were problematic. It also has shared hubs, they too were problematic. I managed to find a port that works GOOD most of the time but occasionally i get sync issues, resetting the MIDI helps, stopping and starting too. I came to realise that the USB port, although it doesn’t share with another USB, it was sharing IRQ with the graphics. A lot of motherboards disregard 1.1 USB and don’t give it the priority it deserves, especially for those like us running a Virus TI, totally integrated.
Regardless to what people say… The TI part WILL work but it can take some effort to get it that way. Some motherboards play ball better than others.