I use a Kensington SlimBlade and it’s apps I guess over-ride the Windows settings allowing for more control. Holding Ctr+alt puts the Slimblade into a very slow fine adjust mode. It also has different user set-ups for corresponding applications. However, unless I’m doing something wrong, once you re-start your PC it defaults to the normal mode, therefore if you open Cubase for example, you have to change the SlimBlade mode.