The routing in the included picture looks fine… What confuses me is you say it wasn’t metering… You should be seeing movement on the lead male track as well as the stereo 1 output bus. So when you play back the audio track, is the “lead male” track meter showing movement? Is the “stereo” track meter showing movement? If so, I would check the cables running from the device to your powered near fields, or if you have an amp, the cables to the amp and the cables to the speakers. Make sure all settings are correct on the mbox, if any need to be made?? Can’t say as I don’t own that device…
I do see some driver issues with the mbox and cubase on a quick google, but those seem like pretty old posts. You could always try the ASIO4all driver and see if it works to rule out a driver issue though.
I’m not surprised it worked easier with protools considering it’s an AVID device, but I can’t imagine them not making the driver compatible.