I am also unable to use the UR22 any longer due to dropouts so I deleted the newest UR22 driver and installed the driver for the UR12 from the disk and started using my UR12. The problem has been solved.
Although this is probably unrelated I thought I would mention it. The UR12 uses RCA connectors and my cable had 1/4" jacks going to speakers without any problems with audio. When I started using the UR22 which has 1/4" audio out, I used the same cable and plugged the RCA end into ROKIT unbalanced receptors, however, this wiring picked up the sounds of the computer’s activity. Going back to the UR12 has solved dropouts and all of the interference.
I have a Lenovo tower with AMD A10-7800 Radeon R7, 12GB Ram with Windows 10.