Another update on this issue:
Deleting this post as that was not the issue. Uninstall and Re-install did not solve the issue. It appears to me that something in the audio bridge is not actually syncing with the drivers. Audio imports do not play, Cubase VSTs do not play nothing. N sound. Only Signal I see is Midi activity in the Midi Monitor. I am about to give up on this. There is something about the Thunderbolt, though as stated, Cubase 8.5.20 works without issue, Studio One v3.3 works without issue and all other audio works without issue, be it standalone VST instruments, windows media…I think you get the point. Any assistance?