I am running two Windows 10 systems 6950x(10core) and 5960x(8core). I had hyperthreading turned off on both. I turned it back on for both and there was no issue as all. It basically cut the CPU idle % by 40-50%. I havent loaded up a large project to stress test it, but overall I think Cubase 10 feels snappier. So, I am happy with that. 