Reviews haven’t really trickled in yet, but I’m betting that the AMD 3970x will be the best performing CPU for the upcoming few months.
You weren’t particularly specific about how you run things but that would be my bet.
I would then just look at the x399 motherboards and pick one with the i/o you need. You should be able to put your OS, samples and projects all on their own M.2 nvme SSDs going straight into the CPU, with several of the motherboards offering an additional 4 M.2 nvme drives on an add-in card, plus of course 6-8 SATA SSDs.
Like I said, reviews for audio aren’t in yet, but I’d be surprised if anything could beat that CPU.