Hello,
after updating the OS everything changes. Please note that Cubase 5 wasn’t made for Windows 10 and its support already ended.
What you need to install:
- Update everything all the way up to its final version Cubase 5.5.3: Cubase 5 Downloads
- eLicenser Control Center
Your soundcard must support ASIO natively on Windows 10. For more information refer to the support page of the interface/soundcard manufacturer.