Well, two developments for me.
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Cubase 9.5.41 worked solidly on my T2 equipped MacBook Pro running the latest Mojave, but only if I removed my Yamaha USB driver - so I couldn’t use my UR824s.
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Bought the Cubase 10 update - works really well on Mojave, and now plays nicely with the Yamaha USB driver! I don’t know what has changed, but for whatever reason, Cubase 10 + Mojave is better than Cubase 9.5.41 + Mojave. I’m happy.
Steve.