I have Cubase 10 and Nuendo 8.3 and there are some things I’m used to now that are Nuendo-only features (at least for now) like: Edit Mode, Direct Routing, Multiple control room outs (to monitor your different submixes).
I adapted this from working with surround mixes and needing to export FullMix, M&E, Dialog, Music, etc. all separately for deliverables:
I’m currently using Direct Routing to make different mixes for Pop library tracks I’m writing for a TV show. So I can click different outputs and monitor my Fullmix, Reduced Mix, Drums&Bass, Drums&Percs mix. Then I can export all the different mixes and hard ending sting in one fell swoop, all named accordingly. Once set up, you can use as a template and you’ll wonder how you ever managed without it! That said, I’m still keeping my Cubase 10 license…just in case 
The higher cost of upgrading Nuendo versions is a good point to consider.